Jinan Youlyy Industrial Co., Ltd.

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Rubber Stopper Formulation Descriptions
- Dec 06, 2017 -

Rubber Stopper Formulation Descriptions


Listed below are the primary stopper formulations with general descriptions.


Gray Bromobutyl/39 with Complete Coat

Pros: low gas and vapor permeability, good for multiple piercing applications,

compatible with most cephalosporin’s, resistant to animal, vegetable, and

mineral oils, good resistance to aliphatic, aromatic and chlorinated solvents.

Cons: not recommended for use with ketones. Can be autoclaved and

irradiated.


Gray Bromobutyl/46

Pros: low gas and vapor permeability, good for multiple piercing applications,

excellent moisture absorption and desorption properties following autoclave

and lyophilization drying cycles. Cons: poor resistance to mineral oil,

aliphatic, aromatic, and chlorinated solvents. Can be autoclaved and

irradiated.


Gray Bromobutyl/47

Pros: low gas and vapor permeability, great for multiple piercing applications

after gamma irradiation, ultra low extractable compound, compatible with

most cephalosporin’s, very good moisture absorption and desorption

properties following autoclave and lyophilization drying cycles, compatible

with WFI applications. Cons: poor resistance to mineral oil, aliphatic,

aromatic, and chlorinated solvents. Can be autoclaved and irradiated.


Gray Bromobutyl/50

Pros: low gas and vapor permeability, very good properties regarding ozone,

animal and vegetable oil. Cons: not good for multiple piercing applications,

poor resistance to mineral oil, aliphatic, aromatic, and chlorinated solvents.

Can be autoclaved.


Gray Chlorobutyl/45

Pros: low gas and vapor permeability, good for multiple piercing applications,

resistant to animal and vegetable oils. Cons: poor resistance to mineral oil,

aliphatic, aromatic, and chlorinated solvents. Can be autoclaved and

irradiated.


Gray Chlorobutyl/46

Pros: low gas and vapor permeability, good for multiple piercing applications,

resistant to animal and vegetable oils, good for lyophilization applications.

Cons: poor resistance to mineral oil, aliphatic, aromatic, and chlorinated

solvents. Can be autoclaved and irradiated.


Gray Chlorobutyl/50

Pros: low gas and vapor permeability, resistant to animal and vegetable oil,

good for lyophilization applications. Cons: poor resistance to mineral oil, aliphatic, aromatic, and chlorinated solvents. Can be autoclaved and irradiated.


Gray Chlorobutyl/55

Pros: low gas and vapor permeability, resistant to animal and vegetable oil,

good for lyophilization applications. Cons: not good for multiple piercing

applications, poor resistance to mineral oil, aliphatic, aromatic, and

chlorinated solvents. Can be autoclaved and irradiated


Gray Chlorobutyl/Isoprene Blend/40 with PTFE Facing

Pros: barrier properties of PTFE, good coring characteristics, fair resistance to

gas and moisture transmission compared to red isoprene. Cons: contains dry

natural rubber. Can be autoclaved.

Gray Chlorbutyl/Isoprene Blend/50

Pros: good coring and reseal characteristics, fair resistance to gas and

moisture transmission compared to red isoprene, good for lyophilization

applications. Cons: contains dry natural rubber. Can be autoclaved.


Black Halobutyl/60

Pros: good resistance to gas and vapor transmission, good for lyophilization

applications. Cons: poor coring and re-seal characteristics, not good for use

with acidic products. Can be autoclaved.


Red Isoprene/45

Pros: good coring and re-seal characteristics. Cons: contains dry natural

rubber, poor resistance to gas and vapor transmission compared to butyl, not

appropriate for products that require an inert gas blanket, not good for use

with acidic products or solvents. Can be autoclaved and irradiated.


Red Natural/40

Pros: good coring and re-seal characteristics. Cons: contains dry natural

rubber, poor gas and vapor transmission compared to butyl, not appropriate

for products that require an inert gas blanket, not good for use with acidic

products or solvents. Can be autoclaved and irradiated.


Pink Natural/48

Pros: good coring and re-seal characteristics. Cons: contains dry natural

rubber, poor gas and vapor transmission compared to butyl, not appropriate

for products that require an inert gas blanket, not good for use with acidic

products or solvents. Can be autoclaved and irradiated.


Natural Silicone/55

Pros: Good for high heat applications, can withstand multiple steam

autoclaves. Cons: very poor barrier to gas and vapor transmission, not

appropriate for products that require an inert gas blanket. Can be autoclaved

and irradiated.


Black Viton®/55

Pros: low gas and vapor permeability, resistant to animal, vegetable and

mineral oil, aliphatic, aromatic, and chlorinated solvents, good for high heat

applications. Cons: not recommended for ketones. Can be autoclaved.


As a manufacturer with first class quality tubular glass vial, aluminum cap, rubber stopper, glass ampoule, glass test tube, prefilled syringe, plastic test tube, plastic cap, screwed vial for over 21 years, and we do have lot of client in over sea market. If anything got your interests after you checked our website, please don't hesitate to contact us.